Short explainers on kinase structure, activation-state classification, and how to get the most out of KinaDB. Video content will be added here as it is produced.
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What is a protein kinase?
The bilobal fold, the ATP pocket, and why conformation matters.
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DFG-in vs DFG-out
How the activation loop defines the active and inactive states.
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Reading a structure page
A tour of the KinaDB structure detail view, field by field.
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Kinase inhibitor types
Type I, Type II, allosteric and covalent inhibitors, explained.
KinaDB — Kinase Structure & Drug Database · Videos